Systematic Literature Review of Imaging Features of Spinal Degeneration in Asymptomatic Populations

Review

doi: x.3174/ajnr.A4173. Epub 2014 Nov 27.

Systematic literature review of imaging features of spinal degeneration in asymptomatic populations

P H Luetmer ² , B Comstock ³ , B W Bresnahan ^four , L Due east Chen ^four , R A Deyo ^five , S Halabi ⁶ , J A Turner ^vii , A L Avins ^viii , K James ⁴ , J T Wald ¹ , D F Kallmes ⁱ , J G Jarvik ^nine

Affiliations

• PMID: 25430861
• PMCID: PMC4464797
• DOI: ten.3174/ajnr.A4173

Complimentary PMC article

Review

Systematic literature review of imaging features of spinal degeneration in asymptomatic populations

Due west Brinjikji  et al. AJNR Am J Neuroradiol. 2015 April .

Free PMC commodity

Abstract

Background and purpose: Degenerative changes are commonly found in spine imaging but often occur in pain-gratis individuals too equally those with back hurting. Nosotros sought to estimate the prevalence, by historic period, of common degenerative spine conditions past performing a systematic review studying the prevalence of spine degeneration on imaging in asymptomatic individuals.

Materials and methods: We performed a systematic review of articles reporting the prevalence of imaging findings (CT or MR imaging) in asymptomatic individuals from published English literature through Apr 2014. Two reviewers evaluated each manuscript. We selected age groupings past decade (xx, 30, 40, l, 60, 70, 80 years), determining age-specific prevalence estimates. For each imaging finding, we fit a generalized linear mixed-effects model for the age-specific prevalence estimate clustering in the study, adjusting for the midpoint of the reported age interval.

Results: Thirty-3 articles reporting imaging findings for 3110 asymptomatic individuals met our study inclusion criteria. The prevalence of deejay degeneration in asymptomatic individuals increased from 37% of 20-year-old individuals to 96% of eighty-yr-sometime individuals. Disk bulge prevalence increased from 30% of those 20 years of historic period to 84% of those eighty years of historic period. Disk protrusion prevalence increased from 29% of those twenty years of historic period to 43% of those 80 years of historic period. The prevalence of annular crack increased from 19% of those 20 years of age to 29% of those 80 years of age.

Conclusions: Imaging findings of spine degeneration are nowadays in high proportions of asymptomatic individuals, increasing with historic period. Many imaging-based degenerative features are likely part of normal aging and unassociated with pain. These imaging findings must be interpreted in the context of the patient's clinical condition.

© 2015 by American Journal of Neuroradiology.

Figures

Fig 1.

Results of literature search.

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Source: https://pubmed.ncbi.nlm.nih.gov/25430861/